The objective of this study was to evaluate the cytotoxicity, antimicrobial and antioxidant activities of extracts of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L. grown in Central Serbia. The content of phenolic compounds in the extracts was determined using spectrophotometric and HPLC analysis. These plant extracts proved to be potent inhibitors of cell growth in the cell lines (FemX and LS 174). The IC50 values against FemX and LS174 cell lines were 33.52 +/- 1.08 and 40.22 +/- 0.03 mu g/mL, respectively. The highest antioxidant capacity was found in C. annuum L. (98.01 +/- 0.72 mu g AA/g) and D. carota L. (48.51 +/- 1.18 mu g AA/g) extracts. The test extracts showed strong to moderate antimicrobial activity (19.53 - 312.50 mu g/mL). D. carota L., L. esculentum Mill. and C. annuum L. extracts can serve as new dietary and food supplements.
Keywords:
Capsicum annuum L. / Daucus carota L. / Lycopersicon esculentum Mill. / Cytotoxicity / Antimicrobial activity / Antioxidant activity
Source:
Bulgarian Chemical Communications, 2015, 47, 1, 38-44
TY - JOUR
AU - Mladenović, Jelena
AU - Radovanović, A.
AU - Pavlović, Radoš
AU - Radovanović, Blaga
AU - Zdravković, Jasmina
AU - Aćamović-Đoković, Gordana
PY - 2015
UR - http://RIVeC.institut-palanka.rs/handle/123456789/167
AB - The objective of this study was to evaluate the cytotoxicity, antimicrobial and antioxidant activities of extracts of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L. grown in Central Serbia. The content of phenolic compounds in the extracts was determined using spectrophotometric and HPLC analysis. These plant extracts proved to be potent inhibitors of cell growth in the cell lines (FemX and LS 174). The IC50 values against FemX and LS174 cell lines were 33.52 +/- 1.08 and 40.22 +/- 0.03 mu g/mL, respectively. The highest antioxidant capacity was found in C. annuum L. (98.01 +/- 0.72 mu g AA/g) and D. carota L. (48.51 +/- 1.18 mu g AA/g) extracts. The test extracts showed strong to moderate antimicrobial activity (19.53 - 312.50 mu g/mL). D. carota L., L. esculentum Mill. and C. annuum L. extracts can serve as new dietary and food supplements.
PB - Bulgarian Academy of Sciences
T2 - Bulgarian Chemical Communications
T1 - Cytotoxicity, antimicrobial and antioxidant activity of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L.
EP - 44
IS - 1
SP - 38
VL - 47
UR - conv_195
ER -
@article{
author = "Mladenović, Jelena and Radovanović, A. and Pavlović, Radoš and Radovanović, Blaga and Zdravković, Jasmina and Aćamović-Đoković, Gordana",
year = "2015",
abstract = "The objective of this study was to evaluate the cytotoxicity, antimicrobial and antioxidant activities of extracts of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L. grown in Central Serbia. The content of phenolic compounds in the extracts was determined using spectrophotometric and HPLC analysis. These plant extracts proved to be potent inhibitors of cell growth in the cell lines (FemX and LS 174). The IC50 values against FemX and LS174 cell lines were 33.52 +/- 1.08 and 40.22 +/- 0.03 mu g/mL, respectively. The highest antioxidant capacity was found in C. annuum L. (98.01 +/- 0.72 mu g AA/g) and D. carota L. (48.51 +/- 1.18 mu g AA/g) extracts. The test extracts showed strong to moderate antimicrobial activity (19.53 - 312.50 mu g/mL). D. carota L., L. esculentum Mill. and C. annuum L. extracts can serve as new dietary and food supplements.",
publisher = "Bulgarian Academy of Sciences",
journal = "Bulgarian Chemical Communications",
title = "Cytotoxicity, antimicrobial and antioxidant activity of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L.",
pages = "44-38",
number = "1",
volume = "47",
url = "conv_195"
}
Mladenović, J., Radovanović, A., Pavlović, R., Radovanović, B., Zdravković, J.,& Aćamović-Đoković, G.. (2015). Cytotoxicity, antimicrobial and antioxidant activity of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L.. in Bulgarian Chemical Communications
Bulgarian Academy of Sciences., 47(1), 38-44.
conv_195
Mladenović J, Radovanović A, Pavlović R, Radovanović B, Zdravković J, Aćamović-Đoković G. Cytotoxicity, antimicrobial and antioxidant activity of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L.. in Bulgarian Chemical Communications. 2015;47(1):38-44.
conv_195 .
Mladenović, Jelena, Radovanović, A., Pavlović, Radoš, Radovanović, Blaga, Zdravković, Jasmina, Aćamović-Đoković, Gordana, "Cytotoxicity, antimicrobial and antioxidant activity of Daucus carota L., Lycopersicon esculentum Mill. and Capsicum annuum L." in Bulgarian Chemical Communications, 47, no. 1 (2015):38-44,
conv_195 .
