@article{
author = "Stefanović, Olgica and Rakonjac, Aleksandra and Nikodijević, Danijela and Milojević, Sara and Dinić, Anica and Simić, Snežana",
year = "2024",
abstract = "We examined potential biological activities of two taxa of freshwater algae, Cladophora glomerata and Vaucheria sp., from Serbia. The total phenolic and pigment contents, antioxidant potential, antimicrobial, antibiofilm activities, and cytotoxicity of the ethanol and acetone extracts were evaluated. The extracts were also subjected to Fourier transform infrared spectroscopy (FTIR) analysis. The levels of total phenolic compounds, chlorophylls a and b, and carotenoids varied based on both the algal taxa and the type of extracts. FTIR analysis showed the presence of lipids, unsaturated fatty acids, protein, carbohydrates, and phenols in the algal extracts. The extracts had moderate DPPH radical scavenging activity and lower reducing power compared with ascorbic acid. The antimicrobial activity expressed as minimum inhibitory concentrations ranged from 0.31 mg/mL to 10 mg/mL. The strains of Staphylococcus aureus and Bacillus cereus isolated from food samples, as well as S. aureus ATCC 25923, were the most sensitive. For the first time, the antibiofilm activity test revealed 98.7% inhibition of S. aureus biofilm formation. The extracts exhibited cytotoxic effects on choriocarcinoma JAR cells but without selectivity on normal fetal lung fibroblast MRC-5 cells. This is the first report on the biological activities of freshwater macroalgae from Serbia.",
publisher = "Beograd : Serbian Biological Society, Beograd : Institute for Biological Research "Siniša Stanković", Beograd : University of Belgrade, Faculty of Biology, Department of Biology and Ecology, Novi Sad : University of Novi Sad, Faculty of Science, Institute for the Application of Nuclear Energy",
journal = "Archives of Biological Sciences",
title = "Freshwater algae Cladophora glomerata and Vaucheria sp. from Serbia as sources of bioactive compounds: chemical analysis and biological activities",
pages = "189-175",
number = "2",
volume = "76",
doi = "10.2298/ABS240215012S"
}